Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?
Published: November 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.5103
Isabella Piva, Giuseppe Lo Monte, Angela Graziano, Roberto Marci
1. Faculty, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
2. Faculty, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
3. Faculty, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
4. Professor, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Correspondence
Dr. Roberto Marci,
Professor, Department of Morphology, Surgery and Experimental Medicine,
Ferrara University, Corso Giovecca 183, 44100, Ferrara, Italy.
Phone : +393386960872, Fax +390532203844, E-mail : roberto.marci@unife.it
Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was achieved via egg donation and in vitro fertilisation (IVF). The disease appeared at 26 weeks and 6 days of gestation and subsequently worsened despite the administration of oral and topic corticosteroids. A healthy baby was delivered at 35 weeks and 2 days of gestation by elective cesarean section and the clinical manifestations resolved in the postpartum period.
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